元件指南

VectorBuilder提供了许多常用的载体元件,可供用户在设计载体时进行选择。下表按类型提供了这些常用元件的详细信息。
重链恒定区(CH)
姓名描述Application NotesReferences序列
hlgG1-CHHuman IgG1 heavy chain constant regionEncodes the constant region of the human IgG1 heavy chain.Nucleic Acids Res. 10:4071 (1982); J Virol. 93:e02270 (2019); View
mlgG1-CHMouse IgG1 heavy chain constant regionEncodes the constant region of the mouse IgG1 heavy chain.Proc Natl Acad Sci U S A. 1980 Apr; 77(4): 2143–2147. View
mlgG2a-CHMouse IgG2a heavy chain constant regionEncodes the constant region of the mouse IgG2a heavy chain.Proc Natl Acad Sci U S A. 78: 4495 (1981) View
mlgG2b-CHMouse IgG2b heavy chain constant regionEncodes the constant region of the mouse IgG2b heavy chain.Proc Natl Acad Sci U S A. 78: 4495 (1981) View
轻链恒定区(CL)
姓名描述Application NotesReferences序列
hIgκ-CLHuman immunoglobulin kappa light chain constant regionEncodes the constant region of the human kappa light chain.Cell. 22(1 Pt 1):197 (1980); Appl Microbiol Biotechnol. 102:5953 (2018); J Virol. 93: e02270 (2019) View
hIgλ2-CLHuman immunoglobulin lambda 2 light chain constant regionEncodes the constant region of the human lambda 2 light chain.Immunogenetics. 25:63 (1987); J Immunol. 169:271 (2002); Acta Pharm Sin B. 9:960 (2019) View
mIgκ-CLMouse immunoglobulin kappa light chain constant region Encodes the constant region of the mouse kappa light chain.Cell. 22(1 Pt 1):197 (1980); Curr Biol. 25:R820 (2015) View
mIgλ1-CLMouse immunoglobulin lambda 1 light chain constant regionEncodes the constant region of the mouse lambda 1 light chain.Nature. 298:380 (1982) View
mIgλ2-CLMouse immunoglobulin lambda 2 light chain constant regionEncodes the constant region of the mouse lambda 2 light chain.Nucleic Acids Res. 10:3831 (1982) View