与云舟生物的合作相当棒！mRNA作为当今的热门疫苗技术，大量被用于多种传染性和非传染性疾病的预防和治疗。云舟生物的Daniel Meng研发团队为我快速搭建了一个IVT mRNA CRO平台，通过与他们的紧密合作我们共同开发了针对HIV和流感的mRNA疫苗。他们的科学专业性与问题解决能力让我印象深刻。云舟生物再一次向我证明他们是值得信赖的合作伙伴。
For several years we have used VectorBuilder for generating expression constructs and custom AAVs. Designing constructs is easy – either use the website or send a request of what you want by email - detailed construct designs are usually in your inbox within 24 hrs. Prices, turnaround times and quality of product mean that ordering from VectorBuilder is just the obvious decision to make when planning experiments. I recommend their services to all my friends.
Rich selection of epitope-tags and promoters help you quick design custom vectors. I no longer waste my time to look into such information. VectorBuilder's design portal is convenient and useful.
Vectorbuilder's service is extremely consistent. We started with regular plasmids and AAV plasmids. Since last year we have ordered many piggybac plasmids. All worked as expected.
We have successfully generated several vectors with VectorBuilder and very much hope there will be many more to come. Their website is very easy to navigate. Timing is really appealing and the prices are convenient. Special thanks to Shelley Wu, the service rep in San Diego. She is extremely helpful and approachable. Overall, VectorBuilder is a huge help!
The straightforward, intuitive interface allowed me to design my construct, by a simply copying-and-pasting sequence of my gene and choosing the right promoter and reporter from an impressive scroll down menu. The vector and recombinant viruses were made on time at a very competitive price with no extra cost for aliquoting into working aliquots. I highly recommend VectorBuilder for a complete recombinant virus production pipeline.
VectorBuilder has been the partner every researcher would wish for during those dark moments of paper revision. They offer the complete package: a wide range of viral vector design options, an extremely user-friendly and intuitive website, direct communication, personal and knowledgeable step-by-step guidance throughout the designing and ordering process, accountability, amazing discounts, unique customer support, fast shipping, and guaranteed virus titers and efficiency. So here’s my big thumbs up for a great product and service provider who has proven indispensable in addressing my research questions!
VectorBuilder has provided incredible value and customer service throughout the entire process from product selection, custom design assistance, order submission, status reports and ultimate delivery management. The custom products I purchased from them performed exactly as advertised and in fact surpassed my expectations. I would recommend VectorBuilder to anyone requiring this type of product.
It has been a great experience working with Vectorbuilder! Their assistance has helped me concentrate on answering biological questions rather than dealing with the hassle of cloning. Vectorbuilder's friendly representatives and timely delivery make the processes easy.
I readily recommend a Vector Builder. My company has used them to produce research great plasmids and AAV vectors. They are helpful and responsive and have always delivered on time and on budget.
We do frequent new vector design and creation for our products. I ordered several custom vectors from Vector Builder using their evolutional platform. That platform is easy to put my gene interested and indicator. They synthesis, sequencing my genes to verify their sequence no mistake and make plasmid for me. Everything is wonderful. More important is the vector expression at high level to meet my requirement. I really recommend to use Vector Builder as your vector designing and creating candidate.
The services provided by VectorBuilder are excellent. I had a few vector constructs made by the VectorBuilder. The description of the constructs by their software is excellent. The technical team of the company seems to have a sound knowledge and the technical suggestion regarding vector construction given to me by them were excellent.
I ordered the cloning of a large gene (about 6 kbp) to the plasmid. VectorBuilder provided the construct with a correct sequence at a reasonable price. So I strongly recommend VectorBuilder's services for cloning of large genes.
NLRP3 inflammasome activation through heart-brain interaction initiates cardiac inflammation and hypertrophy during pressure overload
Preneoplastic stromal cells promote BRCA1-mediated breast tumorigenesis
Schwann cell insulin-like growth factor receptor type-1 mediates metastatic bone cancer pain in mice
Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
Glioblastoma remodelling of human neural circuits decreases survival
DNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
In situ FRET-based localization of the N terminus of myosin binding protein-C in heart muscle cells
PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance
An AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept
Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy homeostasis
Dedifferentiation maintains melanocyte stem cells in a dynamic niche
Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice
SERCA2 phosphorylation at serine 663 is a key regulator of Ca2+ homeostasis in heart diseases
Chaperone-mediated autophagy promotes PCa survival during ARPI through selective proteome remodeling
The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse
Somatic mutations can induce a noninflflamed tumour microenvironment via their original gene functions, despite deriving neoantigens
A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells
Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
Stromal changes in the aged lung induce an emergence from melanoma dormancy
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Modulation of the HIF2α-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis
Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy