服务商工作站 >>
云舟学堂
{['Popular tags' | boatFixI18n | translate]}:
{[tag | boatFixI18n | translate]}
关键词: Therapeutic development, cell and gene therapy, vector design
In today’s high-stakes cell and gene therapy (CGT) landscape, where capital is fleeting and timelines are tight, success favors those who treat vector candidate selection as a scalable science, not an academic gamble.
阅读更多 ››
关键词: CRISPR-Cas9, genome editing, CRISPR vector design, gene knockout, gene regulation
An overview of CRISPR-Cas9 tools and mechanisms, with practical tips to optimize vector design for efficient genome editing.
阅读更多 ››
关键词: Oncolytic virus, tumor targeting, immune stimulation
A deep dive into the attributes and design of recombinant viruses for use as potent oncolytic agents in the clinic and why HSV and VACV are ideal oncolytic virus candidates.
阅读更多 ››
关键词: CAR-T cell therapy, Kymriah CAR-T, immunotherpy
A deep dive into the biology behind CAR-T vectors, their clinical applications, and how CRISPR/Cas9 is being used to create the next generation of CAR therapeutics.
阅读更多 ››
关键词: VSV immunotherapy, oncolytic virus, pseudotyping
Vesicular stomatitis virus (VSV), known for its simplicity and well-explored biology, serves as an invaluable model in virology, particularly through pseudotyping, where its envelope protein is swapped with that of another virus.
阅读更多 ››
关键词: Viral gene therapy, retrovirus, transient transfection
A comprehensive guide to selecting the appropriate viral vector for gene delivery experiments. The article examines how factors such as cell type, expression type, and insert size can impact your experiment while comparing the integration capabilities, carrying capacities, and tropisms of different viruses.
阅读更多 ››
关键词: Zolgensma mechanism, spinal muscular atrophy
Learn about spinal muscular atrophy from a genetic perspective and the mechanisms behind two key gene therapy treatments, Spinraza and Zolgensma.
阅读更多 ››
关键词: Zynteglo gene therapy, beta thalassemia
Learn about the genetic blood disorder beta thalassemia and the lentiviral and CRISPR/Cas9-based gene therapy approaches for treatment.
阅读更多 ››
关键词: Muscular dystrophy, gutless adenovirus, gene therapy
Learn about exciting gene therapy approaches utilizing AAV, adenovirus and gutless adenovirus for treating Duchenne muscular dystrophy.
阅读更多 ››