HUMAN SIRT1

Human SIRT1常用载体

基因信息

  • 基因符号SIRT1
  • 物种 Human (Homo sapiens)
  • 基因全称sirtuin 1
  • 别名SIR2; SIR2L1; SIR2alpha
  • 其他描述NAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacylase sirtuin-1; SIR2-like protein 1; regulatory protein SIR2 homolog 1; sirtuin type 1
  • 载体基本信息
    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
  • NCBI基因ID23411
  • RefSeq转录本
  • RefSeq蛋白
  • 外部链接NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View
  • 查看基因编码

常用载体产品(该类载体有库存现货)

Gene Expression Vectors
该种预制载体通过载体家的骨架制备,采用广泛表达启动子驱动您的目标基因ORF表达。载体标签(如EGFP)已被添加到载体骨架。
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称载体类型 Knockdown Score 标记基因价格
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