HUMAN EGFR

Human EGFR常用载体

基因信息

  • 基因符号EGFR
  • 物种 Human (Homo sapiens)
  • 基因全称epidermal growth factor receptor
  • 别名ERBB; ERBB1; ERRP; HER1; NISBD2; PIG61; mENA
  • 其他描述epidermal growth factor receptor; EGFR vIII; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor tyrosine kinase domain; erb-b2 receptor tyrosine kinase 1; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
  • 载体基本信息
    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020] Annotation information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response.
  • NCBI基因ID1956
  • RefSeq转录本
  • RefSeq蛋白
  • 外部链接NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View
  • 查看基因编码

常用载体产品(该类载体有库存现货)

Gene Expression Vectors
该种预制载体通过载体家的骨架制备,采用广泛表达启动子驱动您的目标基因ORF表达。载体标签(如EGFP)已被添加到载体骨架。
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称载体类型 Knockdown Score 标记基因价格
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