Human APP常用载体

Gene Information

  • Offical Gene Symbol APP
  • Species Human (Homo sapiens)
  • Offical Full Name amyloid beta precursor protein
  • 别名 AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4
  • Other Desigations amyloid-beta A4 protein; alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid precursor protein; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; cerebral vascular amyloid peptide; peptidase nexin-II; protease nexin-II; testicular tissue protein Li 2
  • NCBI基因ID 351
  • 载体基本信息
    This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
  • NCBI  | OMIM  | HGNC  | Ensembl

常用载体产品 (These vectors are available immediately)

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称 载体类型 Knockdown Score
{[ item.alias ]} {[ item.vector_type ]} {[ item.vector_type | boatFixI18nName: 'vectorSystem' | translate ]} {[ item.intrinsic_score ]}
View / Edit Vector 

Can’t find desired vectors above? Use options below to obtain custom vectors.

设计我的载体

使用此选项设计载体并购买质粒构建及相应病毒包装服务

您可以在这里申请克隆和病毒包装的载体服务。

发送设计咨询

使用此选项让我们的专家免费为您设计载体,您也可以购买以下服务:

您可以在这里提交其他服务咨询,包括:

  • 病毒包装
  • CRISPR打靶
  • BAC 修饰
  • 文库构建
  • 质粒抽提
  • 体外转录
  • 诱导突变
  • 更多...