Human AGT常用载体

Gene Information

  • Offical Gene Symbol AGT
  • Species Human (Homo sapiens)
  • Offical Full Name angiotensinogen
  • 别名 ANHU; SERPINA8; hFLT1
  • Other Desigations angiotensinogen; alpha-1 antiproteinase, antitrypsin; angiotensin I; angiotensin II; fetal-liver predominant transporter 1; pre-angiotensinogen; serine (or cysteine) proteinase inhibitor; serpin A8; serpin peptidase inhibitor, clade A, member 8
  • NCBI基因ID 183
  • 载体基本信息
    The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
  • NCBI  | OMIM  | HGNC  | Ensembl

常用载体产品 (These vectors are available immediately)

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称 载体类型 Knockdown Score
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