Human ACE常用载体

Gene Information

  • Offical Gene Symbol ACE
  • Species Human (Homo sapiens)
  • Offical Full Name angiotensin I converting enzyme
  • 别名 ACE1; CD143; DCP; DCP1
  • Other Desigations angiotensin-converting enzyme; CD143 antigen; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin converting enzyme, somatic isoform; carboxycathepsin; dipeptidyl carboxypeptidase 1; dipeptidyl carboxypeptidase I; kininase II; peptidase P
  • NCBI基因ID 1636
  • 载体基本信息
    This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
  • NCBI  | OMIM  | HGNC  | Ensembl

常用载体产品 (These vectors are available immediately)

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称 载体类型 Knockdown Score
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