PIKA OAZ3

Pika OAZ3常用载体

Gene Information

  • Offical Gene Symbol OAZ3
  • Species Pika (Ochotona princeps)
  • Offical Full Name -
  • 别名 -
  • Other Desigations ornithine decarboxylase antizyme 3
  • 载体基本信息
    The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 3, the third member of the antizyme family. Like antizymes 1 and 2, antizyme 3 inhibits ODC activity and polyamine uptake, however, it does not stimulate ODC degradation. Also, while antizymes 1 and 2 have broad tissue distribution, expression of antizyme 3 is restricted to haploid germ cells in testis, suggesting a distinct role for this antizyme in spermiogenesis. Antizyme 3 gene knockout studies in mice showed that homozygous mutant male mice were infertile, and indicated the likely role of this antizyme in the formation of a rigid connection between the sperm head and tail during spermatogenesis. This transcript initiates translation from a non-AUG (CUG) start codon that is highly conserved amongst the antizyme 3 orthologs. [provided by RefSeq, Aug 2014]
  • NCBI基因ID 101534879
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI

常用载体产品

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称 载体类型 Knockdown Score Marker 价格
{[ item.alias ]} {[ item.vector_type ]} {[ item.vector_type | boatFixI18nName: 'vectorSystem' | translate ]} {[ item.intrinsic_score ]} {[ item.marker || '-' ]} ¥{[ item.price || '' ]}
查看载体 

Can’t find desired vectors above? Use options below to obtain custom vectors.

设计我的载体

使用此选项设计载体并购买质粒构建及相应病毒包装服务

您可以在这里申请克隆和病毒包装的载体服务。

发送设计咨询

使用此选项让我们的专家免费为您设计载体,您也可以购买以下服务:

您可以在这里提交其他服务咨询,包括:

  • 病毒包装
  • CRISPR打靶
  • BAC 修饰
  • 文库构建
  • 质粒抽提
  • 体外转录
  • 诱导突变
  • 更多...