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HUMAN EP300

Human EP300常用载体

基因信息

  • 基因符号EP300
  • 物种 Human (Homo sapiens)
  • 基因全称E1A binding protein p300
  • 别名KAT3B; MKHK2; RSTS2; p300
  • 其他描述histone acetyltransferase p300; E1A-associated protein p300; E1A-binding protein, 300kD; histone butyryltransferase p300; histone crotonyltransferase p300; p300 HAT; protein 2-hydroxyisobutyryltransferase p300; protein lactyltransferas p300; protein propionyltransferase p300
  • 载体基本信息
    This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
  • NCBI基因ID2033
  • RefSeq转录本
  • RefSeq蛋白
  • 外部链接NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • 查看基因编码

常用载体产品（该类载体有库存现货）

Gene Expression Vectors
该种预制载体通过载体家的骨架制备，采用广泛表达启动子驱动您的目标基因ORF表达。载体标签（如EGFP）已被添加到载体骨架。
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称载体类型 Knockdown Score 标记基因价格
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