HUMAN EP300

Human EP300常用载体

Gene Information

  • Offical Gene Symbol EP300
  • Species Human (Homo sapiens)
  • Offical Full Name E1A binding protein p300
  • 别名 KAT3B; RSTS2; p300
  • Other Desigations histone acetyltransferase p300; E1A-associated protein p300; E1A-binding protein, 300kD; histone butyryltransferase p300; histone crotonyltransferase p300; p300 HAT; protein propionyltransferase p300
  • 载体基本信息
    This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
  • NCBI基因ID 2033
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

常用载体产品

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称 载体类型 Knockdown Score Marker 价格
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