I have been working with VectorBuilder from the beginning of my postdoc. I’ve chosen VectorBuilder because of the online platform to create customized vectors. It is really impressive how easy is to digitally clone and the order process. Specifically, in our paper, we’ve used VectorBuilder for several critical experiments, including the downregulation of Bassoon protein (AAV-shRNA) and to study the role of Bassoon in the propagation of tau (AAV-GFP-P2A-hTau). These experiments were extremely important to probe our hypothesis.
Dr. Pablo A. Martínez
Indiana University School of Medicine, USA
It has been a great experience working with VB. I was one of the first to test their empty capsid (AAV VLP) service. For my batch capsids were nearly completely empty (>97% by AUC and TEM) and were thus a huge help for assay development as a negative control. I also want to highlight that my contact Matthew Wheeler was always very helpful and transparent for any queries I had and that the team is very agile. A big plus is also the very intuitive website. Overall, a big thumbs up for VectorBuilder from my side.
Dr. Andrei Hutanu
Analytical Biochemist & QC Method Development, Roche, Switzerland
We requested a custom AAV (4-YF) from VectorBuilder. The ordering process was easy and the customer support team were really helpful. Our virus had the expected titer and worked extremely well for our chosen application.
The University of Manchester, UK
VectorBuilder has provided very satisfactory service in making various AAV vector constructs for us. The new sales representative is very proactive in offering help on explaining and introducing other VectorBuilder service to us. Expecting to get more support and service from VectorBuilder.
University of Texas Medical School at Ho, USA
Vector Builder was fast, efficient and easy to use. We received our viral vector promptly and AAV9 has performed exactly how'd we hoped. Thank you!
University of Kentucky, USA
Lis R et al.
Nature. 545: 439 （2017）
Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
Thomas CA et al.
Cell Stem Cell. 21: 319 （2017）
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation.