It has been a great experience working with VB. I was one of the first to test their empty capsid (AAV VLP) service. For my batch capsids were nearly completely empty (>97% by AUC and TEM) and were thus a huge help for assay development as a negative control. I also want to highlight that my contact Matthew Wheeler was always very helpful and transparent for any queries I had and that the team is very agile. A big plus is also the very intuitive website. Overall, a big thumbs up for VectorBuilder from my side.
Dr. Andrei Hutanu
Analytical Biochemist & QC Method Development, Roche, Switzerland
Our laboratory has had great success with both viral constructs and ready-to-use virus prepared by VectorBuilder. They provide excellent customer service at a reasonable price, and their website is extremely user-friendly. Very pleased we discovered this company.
Weill Cornell Medical College, USA
Vector Builder was fast, efficient and easy to use. We received our viral vector promptly and AAV9 has performed exactly how'd we hoped. Thank you!
University of Kentucky, USA
We recently purchased a lentiviral plasmid for constitutive expression of GFP and luciferase and the corresponding lentivirus from VectorBuilder. We have infected several tumor cell lines with excellent results. The lentiviral stocks worked very nicely, saving us a lot of time. We are now using these modified cell lines for monitoring tumor growth in animal models using in vivo imaging.
Research institute for Rare Diseases, Spain
I have been using ready-to-use lentiviruses from Vectorbuilder and they are working great. I used them against iPSC-derived neurons, and the transduction and expression of transgenes are remarkable. The vector backbones provide multiple options to tag your GOIs with fluorescent proteins or implement antibiotic selection markers. Their vector designing tools are helpful. Customer service is reliable. Good luck!
University of California San Diego, USA
I used the lentivirus packaging service from VectorBuilder, and the process is very easy. All I needed to do is to ship a small quantity of transfer plasmid, and VectorBuilder will do the rest. Then I received the high titer virus at the end.
UT MD Anderson Cancer Center, USA
We were searching for a way to outsource the cloning of our vectors and we are very happy with the service. The versatility of the tools make it a great time saver and the vectors were delivered on-time. Lentiviruses packaged are also very reliable and have been very successful in transduction studies in primary cells. Great customer service with fast response times and the team at VectorBuilder are very knowledgeable.
Aridis Pharmaceuticals, USA
We ordered adenovirus from Vectorbuilder company to overexpress our interest genes. The service is fast, considerate, and high-qualified. Besides, the adenovirus is very effective to overexpress our target gene.
Texas A&M University, USA
We ordered adenovirus from VectorBuilder to overexpress our protein of interest in primary mouse hepatocytes. The ordering process, including vector design, was very fast and easy. We received the plasmid and adenovirus within the time frame that was stated during the ordering process and the transduction efficiency of the adenovirus was very high, enabling us to use a low MOI. As a bonus, we also received the control Ad-EGFP adenovirus for free. In the future, I will not use any more siRNA or classical transfection methods on primary mouse hepatocytes, just adenoviruses from VB! I can highly recommend VectorBuilder's services for vector design and adenovirus production.
University of Würzburg, Germany
Lis R et al.
Nature. 545: 439 （2017）
Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
Thomas CA et al.
Cell Stem Cell. 21: 319 （2017）
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation.