与云舟生物的合作相当棒！mRNA作为当今的热门疫苗技术，大量被用于多种传染性和非传染性疾病的预防和治疗。云舟生物的Daniel Meng研发团队为我快速搭建了一个IVT mRNA CRO平台，通过与他们的紧密合作我们共同开发了针对HIV和流感的mRNA疫苗。他们的科学专业性与问题解决能力让我印象深刻。云舟生物再一次向我证明他们是值得信赖的合作伙伴。
Dr. Caijun Sun
Before using VectorBuilder, producing lentiviral overexpression vectors for our in vitro models was a recurring and time-consuming enterprise. We faced frequent challenges in every experimental step, which made it difficult to plan the actual experiments. Setting up the process with VectorBuilder was very efficient, thanks to their great expertise and support. Once we started using VectorBuilder's services, we noticed a substantial increase in productivity as well as a more uniform and predictable transduction pattern of our target cells.
We went on to use VectorBuilder for a large-scale CRISPR screen with a custom library spanning over 1,600 genes. With the provided virus, we were able to easily maintain cell representation and we derived a number of interesting hit genes, which we are excited to follow up on. A big thank you to the entire VectorBuilder Team!
University of Basel
Lis R et al.
Nature. 545: 439 （2017）
Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
Thomas CA et al.
Cell Stem Cell. 21: 319 （2017）
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation.