Popular Vectors for Gene (hOSKM)

基因信息

基因名称hOSKM
类型ORF
子类Pluripotency gene
描述A combination of four reprogramming factor genes (human Oct4, Sox2, Klf4 and c‐Myc) linked by three 2A “self-cleaving” peptides. Involved in reprogramming, or generation of induced pluripotent stem (iPS) cells. Their expression commonly increases in metastatic cancers.
应用注释Required for the maintenance of stem cell properties. It can prevent ES cell differentiation and maintain ES cell self-renewal and pluripotency. Can be used to reprogram both embryonic and adult somatic cells.
参考文献Stem Cells Int. 2016:9451492 (2016); Stem Cells Int. 2019: 1393791 (2019)
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载体描述	载体类型	标记基因
hOSKM expression regular plasmid 载体	Mammalian Gene Expression Vector 指南
hOSKM expression lentivirus 载体	Mammalian Gene Expression Lentiviral Vector 指南
hOSKM expression adenovirus 载体	Mammalian Gene Expression Adenoviral Vector 指南
hOSKM expression AAV病毒载体载体	Mammalian Gene Expression AAV Vector 指南	--
hOSKM expression PiggyBac转座载体载体	Mammalian Gene Expression PiggyBac Vector 指南

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