Human MYC常用载体

Gene Information

  • Offical Gene Symbol MYC
  • Species Human (Homo sapiens)
  • Offical Full Name MYC proto-oncogene, bHLH transcription factor
  • 别名 MRTL; MYCC; bHLHe39; c-Myc
  • Other Desigations myc proto-oncogene protein; avian myelocytomatosis viral oncogene homolog; class E basic helix-loop-helix protein 39; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
  • NCBI基因ID 4609
  • 载体基本信息
    This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
  • NCBI  | OMIM  | HGNC  | Ensembl

常用载体产品 (These vectors are available immediately)

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称 载体类型 Knockdown Score
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