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HUMAN MYC

Human MYC常用载体

基因信息

  • 基因符号MYC
  • 物种 Human (Homo sapiens)
  • 基因全称MYC proto-oncogene, bHLH transcription factor
  • 别名MRTL; MYCC; bHLHe39; c-Myc
  • 其他描述myc proto-oncogene protein; avian myelocytomatosis viral oncogene homolog; class E basic helix-loop-helix protein 39; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
  • 载体基本信息
    This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
  • NCBI基因ID4609
  • RefSeq转录本
  • RefSeq蛋白
  • 外部链接NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • 查看基因编码

常用载体产品（该类载体有库存现货）

Gene Expression Vectors
该种预制载体通过载体家的骨架制备，采用广泛表达启动子驱动您的目标基因ORF表达。载体标签（如EGFP）已被添加到载体骨架。
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称载体类型 Knockdown Score 标记基因价格
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