Human MDM2常用载体

Gene Information

  • Offical Gene Symbol MDM2
  • Species Human (Homo sapiens)
  • Offical Full Name MDM2 proto-oncogene
  • 别名 ACTFS; HDMX; hdm2
  • Other Desigations E3 ubiquitin-protein ligase Mdm2; MDM2 oncogene, E3 ubiquitin protein ligase; MDM2 proto-oncogene, E3 ubiquitin protein ligase; Mdm2, p53 E3 ubiquitin protein ligase homolog; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; double minute 2, human homolog of; p53-binding protein; oncoprotein Mdm2
  • NCBI基因ID 4193
  • 载体基本信息
    This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
  • NCBI  | OMIM  | HGNC  | Ensembl

常用载体产品 (These vectors are available immediately)

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称 载体类型 Knockdown Score
{[ item.alias ]} {[ item.vector_type ]} {[ item.vector_type | boatFixI18nName: 'vectorSystem' | translate ]} {[ item.intrinsic_score ]}
View / Edit Vector 

Can’t find desired vectors above? Use options below to obtain custom vectors.

设计我的载体

使用此选项设计载体并购买质粒构建及相应病毒包装服务

您可以在这里申请克隆和病毒包装的载体服务。

发送设计咨询

使用此选项让我们的专家免费为您设计载体,您也可以购买以下服务:

您可以在这里提交其他服务咨询,包括:

  • 病毒包装
  • CRISPR打靶
  • BAC 修饰
  • 文库构建
  • 质粒抽提
  • 体外转录
  • 诱导突变
  • 更多...