HUMAN BAX

Human BAX常用载体

Gene Information

  • Offical Gene Symbol BAX
  • Species Human (Homo sapiens)
  • Offical Full Name BCL2 associated X, apoptosis regulator
  • 别名 BCL2L4
  • Other Desigations apoptosis regulator BAX; BCL2 associated X protein; BCL2-associated X protein omega; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; bcl-2-like protein 4; bcl2-L-4
  • 载体基本信息
    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • NCBI基因ID 581
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

常用载体产品

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
哺乳动物shRNA干扰载体
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
载体名称 载体类型 Knockdown Score Marker 价格
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